{"id":2427,"date":"2025-11-10T08:46:47","date_gmt":"2025-11-10T07:46:47","guid":{"rendered":"https:\/\/www.lindacastaneda.com\/?p=2427"},"modified":"2025-11-11T10:08:13","modified_gmt":"2025-11-11T09:08:13","slug":"cuando-la-ia-desnaturaliza-la-ciencia","status":"publish","type":"post","link":"https:\/\/www.lindacastaneda.com\/en\/mushware\/cuando-la-ia-desnaturaliza-la-ciencia\/","title":{"rendered":"When AI \u201cDenaturalising\u201d Science"},"content":{"rendered":"<p><\/p>\n<p data-start=\"388\" data-end=\"902\">Across multiple disciplines \u2014genetics, neuroscience, social sciences, computational fields\u2014 a similar warning has emerged: if AI is used only to <em data-start=\"533\" data-end=\"551\">get things right<\/em> rather than to <em data-start=\"567\" data-end=\"583\">understand why<\/em>, we risk producing statistics that <em data-start=\"619\" data-end=\"625\">look<\/em> like science but do not explain it. Science does not end at the thresholds that statistics reveal; its purpose is to explore, to understand, to propose mechanisms, to infer causes, to generate refutable hypotheses, and to design interventions that work <em data-start=\"881\" data-end=\"889\">beyond<\/em> the dataset.<\/p>\n<p data-start=\"904\" data-end=\"1743\">This debate has history.\u00a0 Just to mention 2 of the authors mentioned it, <strong data-start=\"929\" data-end=\"940\">Breiman<\/strong> spoke of the two cultures \u2014prediction versus inference. At the same time (and this is crucial), it is not enough to look at the algorithm; we must also examine the <em data-start=\"1107\" data-end=\"1123\">infrastructure<\/em> that makes it credible;\u00a0 the team of <strong data-start=\"1150\" data-end=\"1178\">Williamson et al. (2024)<\/strong> show, for instance, how consortia, data architectures and technical apparatuses establish a data-centred epistemology that reframes educational phenomena as molecular-like associations \u201cdiscoverable\u201d through bioinformatics. That sociotechnical choreography grants authority to the algorithmic, displaces social theory, and produces an ontology in which subjects appear entirely surveyable and predictable. But this does not happen only in the social realm; it extends to how we understand the natural world \u2014indeed, to almost any complex sociomaterial context.<\/p>\n<h3><strong data-start=\"1754\" data-end=\"1810\">How to integrate AI without \u201cdenaturalising\u201d science<\/strong><\/h3>\n<figure id=\"attachment_2431\" aria-describedby=\"caption-attachment-2431\" style=\"width: 300px\" class=\"wp-caption alignright\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-2431 size-medium\" src=\"https:\/\/www.lindacastaneda.com\/wp-content\/uploads\/2025\/11\/ChatGPT-Image-17-oct-2025-20_04_11-300x300.png\" alt=\"\" width=\"300\" height=\"300\" srcset=\"https:\/\/www.lindacastaneda.com\/wp-content\/uploads\/2025\/11\/ChatGPT-Image-17-oct-2025-20_04_11-300x300.png 300w, https:\/\/www.lindacastaneda.com\/wp-content\/uploads\/2025\/11\/ChatGPT-Image-17-oct-2025-20_04_11-150x150.png 150w, https:\/\/www.lindacastaneda.com\/wp-content\/uploads\/2025\/11\/ChatGPT-Image-17-oct-2025-20_04_11-768x768.png 768w, https:\/\/www.lindacastaneda.com\/wp-content\/uploads\/2025\/11\/ChatGPT-Image-17-oct-2025-20_04_11-500x500.png 500w, https:\/\/www.lindacastaneda.com\/wp-content\/uploads\/2025\/11\/ChatGPT-Image-17-oct-2025-20_04_11-800x800.png 800w, https:\/\/www.lindacastaneda.com\/wp-content\/uploads\/2025\/11\/ChatGPT-Image-17-oct-2025-20_04_11.png 1024w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><figcaption id=\"caption-attachment-2431\" class=\"wp-caption-text\">Analogy: The fried egg is the classic example of protein denaturalisation.<\/figcaption><\/figure>\n<ol>\n<li data-start=\"1812\" data-end=\"2057\"><strong data-start=\"1812\" data-end=\"1853\">Declare AI\u2019s role in one sentence.<\/strong><br data-start=\"1853\" data-end=\"1856\" \/>\u201cGenerates hypotheses.\u201d \u201cActs as a surrogate model to speed up simulations.\u201d \u201cPrioritises experiments.\u201d<br data-start=\"1959\" data-end=\"1962\" \/>If you write \u201cdiscovers cause,\u201d make sure you can defend a causal design \u2014not just performance.<\/li>\n<li data-start=\"2059\" data-end=\"2310\"><strong data-start=\"2059\" data-end=\"2113\">Position your work on the scientific staircase.<\/strong><br data-start=\"2113\" data-end=\"2116\" \/>Description \u2192 prediction \u2192 mechanism \u2192 intervention\/contrafactual.<br data-start=\"2182\" data-end=\"2185\" \/>Specify where you are and what is missing to move upward (experiments, instruments, DAGs\/causal diagrams, control variables).<\/li>\n<li data-start=\"2312\" data-end=\"2574\"><strong data-start=\"2312\" data-end=\"2343\">Triangulate with theory.<\/strong><br data-start=\"2343\" data-end=\"2346\" \/>Let your pattern converse with existing frameworks: does it confirm, contradict, or extend them?<br data-start=\"2442\" data-end=\"2445\" \/>If it contradicts, state what must be revised and how you will test it <em data-start=\"2516\" data-end=\"2537\">out of distribution<\/em> (a different cohort, site, or team).<\/li>\n<li data-start=\"2576\" data-end=\"2795\"><strong data-start=\"2576\" data-end=\"2626\">Design explanations that support decisions.<\/strong><br data-start=\"2626\" data-end=\"2629\" \/>Feature importance alone is not enough. What plausible mechanism does it suggest? What experiment or quasi-experiment would you run tomorrow to try to falsify it?<\/li>\n<li data-start=\"2797\" data-end=\"3024\"><strong data-start=\"2797\" data-end=\"2833\">Use hybrids when appropriate.<\/strong><br data-start=\"2833\" data-end=\"2836\" \/>Physics- or theory-informed models, biological or organisational constraints embedded in architectures, or AI \u2192 hypothesis \u2192 experiment pipelines.<\/li>\n<\/ol>\n<p>Less \u201coracle\u201d, more cumulative science.<\/p>\n<h3 data-start=\"3031\" data-end=\"3072\"><strong data-start=\"3035\" data-end=\"3072\">Warning signs of denaturalisation<\/strong><\/h3>\n<ul>\n<li data-start=\"3076\" data-end=\"3174\">Success defined only by predictive metrics, with no new hypotheses or criteria for intervention.<\/li>\n<li data-start=\"3177\" data-end=\"3263\">No plan for external or causal validation; everything lives within cross-validation.<\/li>\n<li data-start=\"3266\" data-end=\"3332\">\u201cExplanation\u201d reduced to prose rather than a testable mechanism.<\/li>\n<li data-start=\"3335\" data-end=\"3394\">Change the provider or model and \u201ctruth\u201d changes with it.<\/li>\n<li data-start=\"3397\" data-end=\"3509\">Your design adopts the dominant infrastructure (data\/protocols) uncritically and sidelines the field\u2019s theories.<\/li>\n<\/ul>\n<h3 data-start=\"3516\" data-end=\"3554\"><strong data-start=\"3520\" data-end=\"3554\">How to realign (minimum steps)<\/strong><\/h3>\n<ul>\n<li data-start=\"3558\" data-end=\"3630\">Reframe the goal in scientific terms: <em data-start=\"3596\" data-end=\"3628\">which mechanisms compete here?<\/em><\/li>\n<li data-start=\"3633\" data-end=\"3712\">Add a step: AI \u2192 candidate hypotheses \u2192 selection of 1\u20132 testable hypotheses.<\/li>\n<li data-start=\"3715\" data-end=\"3791\">Plan replications (different site\/time\/cohort\/team) and a robustness test.<\/li>\n<li data-start=\"3794\" data-end=\"3910\">Document limits: this is predictive, not causal inference. Stating that situates the piece; it doesn\u2019t devalue it.<\/li>\n<li data-start=\"3913\" data-end=\"4064\">Examine your infrastructure (\u00e0 la Williamson): what epistemological assumptions does it impose? whom does it serve? what perspectives does it displace?<\/li>\n<\/ul>\n<p data-start=\"4071\" data-end=\"4434\">AI can be a <strong data-start=\"4083\" data-end=\"4097\">microscope<\/strong> \u2014revealing patterns that open new hypotheses\u2014 or an <strong data-start=\"4150\" data-end=\"4160\">oracle<\/strong> \u2014issuing predictions that close down questions.<br data-start=\"4208\" data-end=\"4211\" \/>The first nourishes science; the second denaturalises it.<br data-start=\"4268\" data-end=\"4271\" \/>The difference lies in your design: clear purpose, mechanism in sight, external validation, and decisions you can explain in one sentence to a competent colleague.<\/p>\n<h3 data-start=\"4441\" data-end=\"4464\"><strong data-start=\"4445\" data-end=\"4464\">Further reading<\/strong><\/h3>\n<ul>\n<li data-start=\"4468\" data-end=\"4693\">Breiman, L. (2001). <em data-start=\"4488\" data-end=\"4575\">Statistical Modeling: The Two Cultures (with comments and a rejoinder by the author).<\/em> Statistical Science, 16(3), 199\u2013231. <a class=\"decorated-link\" href=\"https:\/\/doi.org\/10.1214\/ss\/1009213726\" target=\"_new\" rel=\"noopener\" data-start=\"4613\" data-end=\"4691\">https:\/\/doi.org\/10.1214\/ss\/1009213726<\/a><\/li>\n<li data-start=\"4696\" data-end=\"4891\">Brette, R. (2019). <em data-start=\"4715\" data-end=\"4761\">Is coding a relevant metaphor for the brain?<\/em> Behavioral and Brain Sciences, 42, e215. <a class=\"decorated-link\" href=\"https:\/\/doi.org\/10.1017\/S0140525X19000049\" target=\"_new\" rel=\"noopener\" data-start=\"4803\" data-end=\"4889\">https:\/\/doi.org\/10.1017\/S0140525X19000049<\/a><\/li>\n<li data-start=\"4894\" data-end=\"5188\">Williamson, B., Kotouza, D., Pickersgill, M., &amp; Pykett, J. (2024). <em data-start=\"4961\" data-end=\"5047\">Infrastructuring Educational Genomics: Associations, Architectures, and Apparatuses.<\/em> Postdigital Science and Education, 6(4), 1143\u20131172. <a class=\"decorated-link\" href=\"https:\/\/doi.org\/10.1007\/s42438-023-00451-3\" target=\"_new\" rel=\"noopener\" data-start=\"5100\" data-end=\"5188\">https:\/\/doi.org\/10.1007\/s42438-023-00451-3<\/a><\/li>\n<\/ul>\n<p data-start=\"5212\" data-end=\"5489\"><span style=\"color: #800000;\">This text was originally written as one of the <em data-start=\"5262\" data-end=\"5278\">critical boxes<\/em> included in the materials of the CSIC microcredential <strong data-start=\"5333\" data-end=\"5382\">\u201cSolve Digital Challenges Creatively with AI\u201d<\/strong> <em data-start=\"5383\" data-end=\"5409\">(Area \u201cProblem Solving\u201d)<\/em>, to be launched in January 2026, in which I have the pleasure to participate. <\/span><span style=\"color: #800000;\">I am also part of its sister microcredential, <strong data-start=\"5542\" data-end=\"5591\">\u201c<a href=\"https:\/\/aprende.csic.es\/catalogo\/microcredencial-creacion-contenidos-ia\/\" target=\"_blank\" rel=\"noopener\">Create High-Quality Digital Content with AI<\/a>\u201d<\/strong>, open since November 2025. <\/span><span style=\"color: #800000;\">Both belong to the CSIC\u2019s microcredential pathway on Artificial Intelligence and aim to foster an ethical, critical, and creative approach to integrating AI into scientific and professional practice. More info\u00a0 (just in Spanish) at CSIC Aprende Website\u00a0 <a href=\"https:\/\/aprende.csic.es\/\" target=\"_blank\" rel=\"noopener\">https:\/\/aprende.csic.es\/<\/a>,<\/span><\/p>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Across multiple disciplines \u2014genetics, neuroscience, social sciences, computational fields\u2014 a similar warning has emerged: if AI is used only to get things right rather than to understand why, we risk producing statistics that look like science but do not explain it. Science does not end at the thresholds that statistics reveal; its purpose is to <a class=\"read-more\" href=\"https:\/\/www.lindacastaneda.com\/en\/mushware\/cuando-la-ia-desnaturaliza-la-ciencia\/\">Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"episode_type":"","audio_file":"","podmotor_file_id":"","podmotor_episode_id":"","cover_image":"","cover_image_id":"","duration":"","filesize":"","filesize_raw":"","date_recorded":"","explicit":"","block":"","itunes_episode_number":"","itunes_title":"","itunes_season_number":"","itunes_episode_type":"","_vp_format_video_url":"","_vp_image_focal_point":[],"footnotes":""},"categories":[198,18,22,27],"tags":[99,135],"class_list":["post-2427","post","type-post","status-publish","format-standard","hentry","category-ia","category-pedagogia","category-reflexiones","category-trabajos","tag-investigacion","tag-research"],"_links":{"self":[{"href":"https:\/\/www.lindacastaneda.com\/en\/wp-json\/wp\/v2\/posts\/2427","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lindacastaneda.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lindacastaneda.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lindacastaneda.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lindacastaneda.com\/en\/wp-json\/wp\/v2\/comments?post=2427"}],"version-history":[{"count":7,"href":"https:\/\/www.lindacastaneda.com\/en\/wp-json\/wp\/v2\/posts\/2427\/revisions"}],"predecessor-version":[{"id":2469,"href":"https:\/\/www.lindacastaneda.com\/en\/wp-json\/wp\/v2\/posts\/2427\/revisions\/2469"}],"wp:attachment":[{"href":"https:\/\/www.lindacastaneda.com\/en\/wp-json\/wp\/v2\/media?parent=2427"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lindacastaneda.com\/en\/wp-json\/wp\/v2\/categories?post=2427"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lindacastaneda.com\/en\/wp-json\/wp\/v2\/tags?post=2427"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}